2-BFI hydrochloride ( —— )

产品货号. M27593 CAS No. 89196-95-2

COA

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HNMR

HPLC

MSDS

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产品名称

2-BFI hydrochloride
注意事项

本公司产品仅用于科研实验，不得用于人体或动物的临床与诊断
产品简述

2-BFI hydrochloride is a high-affinity agonist of I2-imidazoline receptor. 2-BFI hydrochloride can be used in studies about protection against stroke and acute inflammatory immune disease.
产品描述

2-BFI hydrochloride is a high-affinity agonist of I2-imidazoline receptor. 2-BFI hydrochloride can be used in studies about protection against stroke and acute inflammatory immune disease.(In Vivo):2-BFI hydrochloride administration after dMCAO improved the neurological deficits and decreased the infarct volume. 2-BFI hydrochloride reduced phosphorylation of mTOR and p70S6, increased IL-10 and TGF-β, and decreased IFN-γ levels in ischemic rats. 2-BFI hydrochloride attenuates ischemic injury by inhibiting the activation of mTOR signaling and modulating neuroinflammation after stroke in rats.
同义词

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通路

Others
靶点

Other Targets
受体

BRM/BRG1
研究领域

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适应症

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1.Centore, Richard C. et al. Preparation of BRG1/BRM inhibitors for treating cancer. US20220079940 A1.

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